Adaptive Functionality

Advanced solutions for safeguarding our planet and human health against chemical, biological, and environmental threats.

pH-responsive Microneedles

  • Due to skin moisture, the PVP microneedles rapidly dissolve and release drug-encapsulated ZIF-8.
  • As the inflammation stage begins, the decreased pH triggers drug release from ZIF-8.
CCM@ZIF loaded microneedle release mechanism
pH-responsive ZIF degradation and release analysis

Curcumin/Zeolitic Imidazolate Framework-8 Nanoparticle-Integrated Microneedles for pH-Responsive Treatment of Skin Disorders (2022)

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